Epigenetic interactions during growth enable the skull to respond to mechanical stimuli and to compensate for and coordinate the growth of the various organs that make up the head in order to acquire and/or maintain certain functions.

They enable normal development by controlling bone remodelling. Despite this central role, the importance of these interactions in expressing differences between species and, in the longer term, in clade dynamics remains poorly understood.

The aim here is to study I) the establishment of craniofacial disparity in rodents during development and II) to assess the importance of epigenetic processes during this postnata growth.